Q: How is iron related to Alzheimer’s disease?
A: Excess iron in the brain causes oxidative damage because it reacts with the fats and proteins in brain cells. This process leads to the death of neurons and helps promote the development of Alzheimer’s disease. The damage is most severe in the areas responsible for memory and decision-making.
Q: What did the recent study on iron in the brain and Alzheimer’s discover?
A: The study found that people with Down syndrome and Alzheimer’s had twice as much iron in their brains compared to people with Alzheimer’s alone. The extra iron was linked to a faster and more severe buildup of brain plaques, greater cell damage from stress, and weaker natural protection in the brain.
Q: Where does the excess iron come from?
A: Small, undetected brain hemorrhages (microhemorrhages) appear to be a significant source. When blood leaks into brain tissue, iron from hemoglobin is released and stored in the area, leading to long-term oxidative stress. People with Down syndrome-related Alzheimer’s disease had a threefold increase in the enzyme that processes iron derived from blood, suggesting that chronic internal bleeding promotes iron accumulation.
Q: How can I tell if I have high iron levels?
A: First, have your ferritin level checked, which is the storage form of iron. Ideally, your level should be between 60 and 75 ng/mL. Also, request a GGT test to measure oxidative stress. Elevated ferritin and GGT levels together suggest that your body isn’t handling iron safely, which can affect brain health.
Q: What steps can I take to reduce the risk of brain damage caused by iron?
A: Donate blood regularly or request a therapeutic phlebotomy if your ferritin level is elevated. Balance iron with copper-rich foods or supplements, increase calcium from whole food sources, eliminate vegetable oils, and increase antioxidants such as glutathione. You can also use molecular hydrogen to reactivate antioxidant enzymes and help your brain neutralize oxidative stress.
