
14. Half and Half Nails

Take a look at your nails. Normally, the base of your nail (the lunula) is lighter. However, in some people with chronic kidney disease, the top half of the nail appears pink or brown, while the bottom half is white. These are called half and half nails, and while the exact cause isn’t known, there’s a strong link to kidney issues.
13, 12. Calcinosis Cutis and Artery Calcification

When kidneys can’t get rid of excess phosphate, levels in the blood rise. Phosphate can bind with calcium, forming crystals. If these crystals deposit in the skin, it’s called calcinosis cutis, appearing as hard, painless, whitish-yellow bumps. More concerning, these crystals can deposit in blood vessels, making them hard and less flexible. This artery calcification can be seen on X-rays as the arteries become visible, feeling like a guitar string under the skin. High phosphate also affects calcium levels, which can lead to muscle cramps.
11, 10. Muscle Cramps and Osteoporosis

Low calcium levels, often linked to kidney problems and high phosphate, can cause painful muscle cramps, especially at night. Additionally, the body releases parathyroid hormone to try and get calcium from bones when levels are low. Over time, this weakens bones, leading to osteoporosis. Signs include height loss or fractures from minor falls, particularly in the wrist, spine, or hips.
